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BDBM50047892 4-Hydroxy-2-oxo-1-phenyl-1,2-dihydro-[1,8]naphthyridine-3-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::CHEMBL156176

SMILES: CN1C2CCC1CC(C2)OC(=O)c1c(O)c2cccnc2n(-c2ccccc2)c1=O

InChI Key: InChIKey=UGHLNPUUSKCODF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047892   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50047892
PNG
(4-Hydroxy-2-oxo-1-phenyl-1,2-dihydro-[1,8]naphthyr...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)c1c(O)c2cccnc2n(-c2ccccc2)c1=O |THB:9:7:1:3.4|
Show InChI InChI=1S/C23H23N3O4/c1-25-15-9-10-16(25)13-17(12-15)30-23(29)19-20(27)18-8-5-11-24-21(18)26(22(19)28)14-6-3-2-4-7-14/h2-8,11,15-17,27H,9-10,12-13H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
>100n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.

J Med Chem 36: 617-26 (1993)


BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair