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BDBM50047894 CHEMBL157689::Quinoline-3-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester

SMILES: CN1C2CCC1CC(C2)OC(=O)c1cnc2ccccc2c1

InChI Key: InChIKey=SDOBRINCJGXIRO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50047894
PNG
(CHEMBL157689 | Quinoline-3-carboxylic acid 8-methy...)
Show SMILES CN1C2CCC1CC(C2)OC(=O)c1cnc2ccccc2c1 |THB:9:7:1:3.4|
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 67n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.

J Med Chem 36: 617-26 (1993)


BindingDB Entry DOI: 10.7270/Q25B034N
More data for this
Ligand-Target Pair