BDBM50048181 CHEMBL3310786

SMILES: OC(=O)[C@H]1C[C@@H]1c1nc(SCc2cccc(F)c2F)nc(O)c1C#N

InChI Key: InChIKey=CGWUSHFJEIHQNC-IUCAKERBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50048181 (CHEMBL3310786) Show SMILES OC(=O)[C@H]1C[C@@H]1c1nc(SCc2cccc(F)c2F)nc(O)c1C#N |r| Show InChI InChI=1S/C16H11F2N3O3S/c17-11-3-1-2-7(12(11)18)6-25-16-20-13(8-4-9(8)15(23)24)10(5-19)14(22)21-16/h1-3,8-9H,4,6H2,(H,23,24)(H,20,21,22)/t8-,9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity against human recombinant CXCR2 receptor expressed in CHO cell membranes by SPA based [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 24: 3285-90 (2014) Article DOI: 10.1016/j.bmcl.2014.06.011 BindingDB Entry DOI: 10.7270/Q2930VTJ
					More data for this Ligand-Target Pair