BDBM50048191 CHEMBL444002::N-[6-(4-Methanesulfonyl-phenoxy)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Oc1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=HGISIIZYLGEQSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048191 (CHEMBL444002 | N-[6-(4-Methanesulfonyl-phenoxy)-1-...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Oc1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C17H17NO6S2/c1-25(20,21)13-6-4-12(5-7-13)24-17-10-14-11(3-8-16(14)19)9-15(17)18-26(2,22)23/h4-7,9-10,18H,3,8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair