BDBM50048202 CHEMBL343853::N-[6-(2,4-Difluoro-benzyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Cc1ccc(F)cc1F

InChI Key: InChIKey=UBHILSKDYRUXLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048202 (CHEMBL343853 | N-[6-(2,4-Difluoro-benzyl)-1-oxo-in...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Cc1ccc(F)cc1F Show InChI InChI=1S/C17H15F2NO3S/c1-24(22,23)20-16-8-10-3-5-17(21)14(10)7-12(16)6-11-2-4-13(18)9-15(11)19/h2,4,7-9,20H,3,5-6H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair