BDBM50048207 CHEMBL344351::N-[1-Oxo-6-(pyridin-4-ylsulfanyl)-indan-5-yl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccncc1

InChI Key: InChIKey=ASHXWIUUTZEVNP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048207 (CHEMBL344351 | N-[1-Oxo-6-(pyridin-4-ylsulfanyl)-i...) Show SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Sc1ccncc1 Show InChI InChI=1S/C15H14N2O3S2/c1-22(19,20)17-13-8-10-2-3-14(18)12(10)9-15(13)21-11-4-6-16-7-5-11/h4-9,17H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair