BDBM50048209 CHEMBL358295::N-[6-(4-Methoxy-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES: COc1ccc(Sc2cc3C(=O)CCc3cc2NS(C)(=O)=O)cc1

InChI Key: InChIKey=IPNFBRLFLXHQCM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50048209 (CHEMBL358295 | N-[6-(4-Methoxy-phenylsulfanyl)-1-o...) Show SMILES COc1ccc(Sc2cc3C(=O)CCc3cc2NS(C)(=O)=O)cc1 Show InChI InChI=1S/C17H17NO4S2/c1-22-12-4-6-13(7-5-12)23-17-10-14-11(3-8-16(14)19)9-15(17)18-24(2,20)21/h4-7,9-10,18H,3,8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cells				J Med Chem 38: 4897-905 (1996) BindingDB Entry DOI: 10.7270/Q28051PC
					More data for this Ligand-Target Pair