BDBM50048599 CHEMBL346142::Indazol-1-yl-propyl-pyridin-4-yl-amine; compound with (E)-but-2-enedioic acid

SMILES: CCCN(c1ccncc1)n1ncc2ccccc12

InChI Key: InChIKey=WEMUITQZWVBMLV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50048599 (CHEMBL346142 | Indazol-1-yl-propyl-pyridin-4-yl-am...) Show SMILES CCCN(c1ccncc1)n1ncc2ccccc12 Show InChI InChI=1S/C15H16N4/c1-2-11-18(14-7-9-16-10-8-14)19-15-6-4-3-5-13(15)12-17-19/h3-10,12H,2,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against norepinephrine (NE) uptake in rat whole brain synaptosome preparation				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50048599 (CHEMBL346142 | Indazol-1-yl-propyl-pyridin-4-yl-am...) Show SMILES CCCN(c1ccncc1)n1ncc2ccccc12 Show InChI InChI=1S/C15H16N4/c1-2-11-18(14-7-9-16-10-8-14)19-15-6-4-3-5-13(15)12-17-19/h3-10,12H,2,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against [3H]-NMCC binding to nicotinic receptors in rat cortex				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50048599 (CHEMBL346142 | Indazol-1-yl-propyl-pyridin-4-yl-am...) Show SMILES CCCN(c1ccncc1)n1ncc2ccccc12 Show InChI InChI=1S/C15H16N4/c1-2-11-18(14-7-9-16-10-8-14)19-15-6-4-3-5-13(15)12-17-19/h3-10,12H,2,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinesterase in rat striatal preparation				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50048599 (CHEMBL346142 | Indazol-1-yl-propyl-pyridin-4-yl-am...) Show SMILES CCCN(c1ccncc1)n1ncc2ccccc12 Show InChI InChI=1S/C15H16N4/c1-2-11-18(14-7-9-16-10-8-14)19-15-6-4-3-5-13(15)12-17-19/h3-10,12H,2,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinesterase in rat striatal preparation				J Med Chem 39: 570-81 (1996) Article DOI: 10.1021/jm9506433 BindingDB Entry DOI: 10.7270/Q2BR8R7K
					More data for this Ligand-Target Pair