BDBM50048998 CHEMBL83425::N-Ethyl-N-hydroxy-3-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-propionamide

SMILES: CCN(O)C(=O)CCc1ccc2OCc3ccccc3C(=O)c2c1

InChI Key: InChIKey=ACXDRWHLYHDUEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50048998 (CHEMBL83425 | N-Ethyl-N-hydroxy-3-(11-oxo-6,11-dih...) Show SMILES CCN(O)C(=O)CCc1ccc2OCc3ccccc3C(=O)c2c1 Show InChI InChI=1S/C19H19NO4/c1-2-20(23)18(21)10-8-13-7-9-17-16(11-13)19(22)15-6-4-3-5-14(15)12-24-17/h3-7,9,11,23H,2,8,10,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant				J Med Chem 39: 246-52 (1996) Article DOI: 10.1021/jm950563z BindingDB Entry DOI: 10.7270/Q22806PF
					More data for this Ligand-Target Pair