BDBM50049005 CHEMBL431007::N-Cyclohexyl-N-hydroxy-3-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-propionamide

SMILES: ON(C1CCCCC1)C(=O)CCc1ccc2OCc3ccccc3C(=O)c2c1

InChI Key: InChIKey=JVDHPCPMVPAFOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50049005 (CHEMBL431007 | N-Cyclohexyl-N-hydroxy-3-(11-oxo-6,...) Show SMILES ON(C1CCCCC1)C(=O)CCc1ccc2OCc3ccccc3C(=O)c2c1 Show InChI InChI=1S/C23H25NO4/c25-22(24(27)18-7-2-1-3-8-18)13-11-16-10-12-21-20(14-16)23(26)19-9-5-4-6-17(19)15-28-21/h4-6,9-10,12,14,18,27H,1-3,7-8,11,13,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant				J Med Chem 39: 246-52 (1996) Article DOI: 10.1021/jm950563z BindingDB Entry DOI: 10.7270/Q22806PF
					More data for this Ligand-Target Pair