BDBM50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX

SMILES: Oc1cc2CCC3NCc4ccccc4C3c2cc1O

InChI Key: InChIKey=BGOQGUHWXBGXJW-UHFFFAOYSA-N

Data: 24 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50049047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
Dopamine D1B (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
DRD1 (Monkey)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	58.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by PDSP Ki Database									CNS Drug Rev 10: 230-42 (2004) Article DOI: 10.1111/j.1527-3458.2004.tb00024.x BindingDB Entry DOI: 10.7270/Q2Z89B0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50049047 (5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10...) Show SMILES Oc1cc2CCC3NCc4ccccc4C3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by PDSP Ki Database									Bioorg Med Chem 11: 1451-64 (2003) Article DOI: 10.1016/S0968-0896(02)00561-8 BindingDB Entry DOI: 10.7270/Q2CV4G90
					More data for this Ligand-Target Pair