BDBM50049111 3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-isopropyl-2-propyl-3H-imidazole-4-carboxylic acid::CHEMBL323819

SMILES: CCCc1nc(C(C)C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=XHISRMRFXXRDLA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50049111 (3-(2'-Carboxy-biphenyl-4-ylmethyl)-5-isopropyl-2-p...) Show SMILES CCCc1nc(C(C)C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H26N2O4/c1-4-7-20-25-21(15(2)3)22(24(29)30)26(20)14-16-10-12-17(13-11-16)18-8-5-6-9-19(18)23(27)28/h5-6,8-13,15H,4,7,14H2,1-3H3,(H,27,28)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Company, Ltd. Curated by ChEMBL					Assay Description In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex				J Med Chem 39: 323-38 (1996) Article DOI: 10.1021/jm950450f BindingDB Entry DOI: 10.7270/Q28S4P18
					More data for this Ligand-Target Pair