null
SMILES: CCc1nc(Nc2ccc(CC(O)=O)cc2)nc(n1)-c1ccc(F)cc1
InChI Key: InChIKey=NYCUHTHGIQZFPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50049150 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50049150
(CHEMBL3315255)Show SMILES CCc1nc(Nc2ccc(CC(O)=O)cc2)nc(n1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN4O2/c1-2-16-22-18(13-5-7-14(20)8-6-13)24-19(23-16)21-15-9-3-12(4-10-15)11-17(25)26/h3-10H,2,11H2,1H3,(H,25,26)(H,21,22,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 727 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University
Curated by ChEMBL
| Assay Description Inhibition of human PDE4D |
Bioorg Med Chem Lett 24: 4031-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50049150
(CHEMBL3315255)Show SMILES CCc1nc(Nc2ccc(CC(O)=O)cc2)nc(n1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN4O2/c1-2-16-22-18(13-5-7-14(20)8-6-13)24-19(23-16)21-15-9-3-12(4-10-15)11-17(25)26/h3-10H,2,11H2,1H3,(H,25,26)(H,21,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University
Curated by ChEMBL
| Assay Description Inhibition of human PDE4B |
Bioorg Med Chem Lett 24: 4031-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD |
More data for this Ligand-Target Pair | |