BDBM50049153 CHEMBL3315258
SMILES: OC(=O)Cc1ccc(CNc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1
InChI Key: InChIKey=XVPFCANOIMFWMR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50049153 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50049153
(CHEMBL3315258)Show SMILES OC(=O)Cc1ccc(CNc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1 Show InChI InChI=1S/C21H19ClN4O2/c22-17-3-1-2-16(11-17)20-24-19(15-8-9-15)25-21(26-20)23-12-14-6-4-13(5-7-14)10-18(27)28/h1-7,11,15H,8-10,12H2,(H,27,28)(H,23,24,25,26) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 726 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4D |
Bioorg Med Chem Lett 24: 4031-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.002
BindingDB Entry DOI: 10.7270/Q2KD20KD |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50049153
(CHEMBL3315258)Show SMILES OC(=O)Cc1ccc(CNc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1 Show InChI InChI=1S/C21H19ClN4O2/c22-17-3-1-2-16(11-17)20-24-19(15-8-9-15)25-21(26-20)23-12-14-6-4-13(5-7-14)10-18(27)28/h1-7,11,15H,8-10,12H2,(H,27,28)(H,23,24,25,26) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 845 | n/a | n/a | n/a | n/a | n/a | n/a |
Northern Illinois University
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B |
Bioorg Med Chem Lett 24: 4031-4 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.002
BindingDB Entry DOI: 10.7270/Q2KD20KD |
More data for this
Ligand-Target Pair | |
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