BDBM50049410 CHEMBL3315265

SMILES: OC(=O)c1ccc(Nc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1

InChI Key: InChIKey=HQJJTHYXAGWJCX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50049410 (CHEMBL3315265) Show SMILES OC(=O)c1ccc(Nc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1 Show InChI InChI=1S/C19H15ClN4O2/c20-14-3-1-2-13(10-14)17-22-16(11-4-5-11)23-19(24-17)21-15-8-6-12(7-9-15)18(25)26/h1-3,6-11H,4-5H2,(H,25,26)(H,21,22,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50049410 (CHEMBL3315265) Show SMILES OC(=O)c1ccc(Nc2nc(nc(n2)-c2cccc(Cl)c2)C2CC2)cc1 Show InChI InChI=1S/C19H15ClN4O2/c20-14-3-1-2-13(10-14)17-22-16(11-4-5-11)23-19(24-17)21-15-8-6-12(7-9-15)18(25)26/h1-3,6-11H,4-5H2,(H,25,26)(H,21,22,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human PDE4B				Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD
					More data for this Ligand-Target Pair