null

SMILES: CCc1nc(Nc2ccc(cc2)C(C)(C)C(O)=O)nc(n1)-c1cccc(Cl)c1

InChI Key: InChIKey=FTDOHRLSQMMQMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50049419 (CHEMBL3315276) Show SMILES CCc1nc(Nc2ccc(cc2)C(C)(C)C(O)=O)nc(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C21H21ClN4O2/c1-4-17-24-18(13-6-5-7-15(22)12-13)26-20(25-17)23-16-10-8-14(9-11-16)21(2,3)19(27)28/h5-12H,4H2,1-3H3,(H,27,28)(H,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50049419 (CHEMBL3315276) Show SMILES CCc1nc(Nc2ccc(cc2)C(C)(C)C(O)=O)nc(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C21H21ClN4O2/c1-4-17-24-18(13-6-5-7-15(22)12-13)26-20(25-17)23-16-10-8-14(9-11-16)21(2,3)19(27)28/h5-12H,4H2,1-3H3,(H,27,28)(H,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northern Illinois University Curated by ChEMBL					Assay Description Inhibition of human PDE4B				Bioorg Med Chem Lett 24: 4031-4 (2014) Article DOI: 10.1016/j.bmcl.2014.06.002 BindingDB Entry DOI: 10.7270/Q2KD20KD
					More data for this Ligand-Target Pair