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SMILES: CC(C(=O)NCc1ccc(nc1-c1cc2ccccc2s1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=BAWMELZRCOBQJO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049541   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50049541
PNG
(CHEMBL3317492)
Show SMILES CC(C(=O)NCc1ccc(nc1-c1cc2ccccc2s1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1S/C25H21F4N3O3S2/c1-14(15-7-9-19(18(26)11-15)32-37(2,34)35)24(33)30-13-17-8-10-22(25(27,28)29)31-23(17)21-12-16-5-3-4-6-20(16)36-21/h3-12,14,32H,13H2,1-2H3,(H,30,33)
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Article
PubMed
 1n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity against human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced channel activation by FLIPR assay

Bioorg Med Chem Lett 24: 4044-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.072
BindingDB Entry DOI: 10.7270/Q2JH3NTH
More data for this
Ligand-Target Pair