BDBM50049618 3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide::3-Chloro-4-methoxy-[1,1';2',1'']terphenyl-4''-sulfonic acid amide::CHEMBL54039
SMILES: COc1ccc(cc1Cl)-c1ccccc1-c1ccc(cc1)S(N)(=O)=O
InChI Key: InChIKey=YHPIWFZVGYDONZ-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50049618 (3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1. | J Med Chem 39: 1846-56 (1996) Article DOI: 10.1021/jm950878e BindingDB Entry DOI: 10.7270/Q2Z89BGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50049618 (3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 | J Med Chem 39: 1846-56 (1996) Article DOI: 10.1021/jm950878e BindingDB Entry DOI: 10.7270/Q2Z89BGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50049618 (3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 19.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 2 Curated by ChEMBL | Assay Description Inhibition of human Prostaglandin G/H synthase 2 | J Med Chem 44: 3223-30 (2001) BindingDB Entry DOI: 10.7270/Q2736S4D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase (Homo sapiens (Human)) | BDBM50049618 (3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Binding affinity for Prostaglandin G/H synthase 2 (COX-2) | Bioorg Med Chem Lett 14: 4665-70 (2004) Article DOI: 10.1016/j.bmcl.2004.06.095 BindingDB Entry DOI: 10.7270/Q2Q23ZQZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50049618 (3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Binding affinity for Prostaglandin G/H synthase 1 (COX-1) | Bioorg Med Chem Lett 14: 4665-70 (2004) Article DOI: 10.1016/j.bmcl.2004.06.095 BindingDB Entry DOI: 10.7270/Q2Q23ZQZ | |||||||||||
More data for this Ligand-Target Pair |