BDBM50049686 2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-dioxo-10H-10lambda*6*-thioxanthen-9-one::CHEMBL52887

SMILES: COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1

InChI Key: InChIKey=WLGHRWIMBHLODC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50049686 (2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...) Show SMILES COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 Show InChI InChI=1S/C16H12N4O4S/c1-20-18-16(17-19-20)9-3-5-11-14(7-9)25(22,23)13-6-4-10(24-2)8-12(13)15(11)21/h3-8H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50049686 (2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...) Show SMILES COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 Show InChI InChI=1S/C16H12N4O4S/c1-20-18-16(17-19-20)9-3-5-11-14(7-9)25(22,23)13-6-4-10(24-2)8-12(13)15(11)21/h3-8H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound against rat brain mitochondrial Monoamine oxidase B				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair