BDBM50049764 2-[1-Pyridazin-3-yl-meth-(E)-ylidene]-3,4-dihydro-2H-naphthalen-1-one::CHEMBL166709

SMILES: O=C1\C(CCc2ccccc12)=C\c1cccnn1

InChI Key: InChIKey=QPJAJZLWZJXVSQ-ZRDIBKRKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50049764 (2-[1-Pyridazin-3-yl-meth-(E)-ylidene]-3,4-dihydro-...) Show SMILES O=C1\C(CCc2ccccc12)=C\c1cccnn1 Show InChI InChI=1S/C15H12N2O/c18-15-12(10-13-5-3-9-16-17-13)8-7-11-4-1-2-6-14(11)15/h1-6,9-10H,7-8H2/b12-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50049764 (2-[1-Pyridazin-3-yl-meth-(E)-ylidene]-3,4-dihydro-...) Show SMILES O=C1\C(CCc2ccccc12)=C\c1cccnn1 Show InChI InChI=1S/C15H12N2O/c18-15-12(10-13-5-3-9-16-17-13)8-7-11-4-1-2-6-14(11)15/h1-6,9-10H,7-8H2/b12-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität de Saarlandes Curated by ChEMBL					Assay Description Inhibitory activity against Steroidgenic Cytochrome P450 C18 using Bovine adrenal mitochondria.				J Med Chem 39: 834-41 (1996) Article DOI: 10.1021/jm950377t BindingDB Entry DOI: 10.7270/Q29K499J
					More data for this Ligand-Target Pair