BindingDB logo
myBDB logout

null

SMILES: Fc1ccc(CNC(=O)c2sc3ncccc3c2-c2ccc(F)cc2)cc1

InChI Key: InChIKey=GHDMPHUWTMIYHF-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50050068   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50050068
PNG
(CHEMBL3317721)
Show SMILES Fc1ccc(CNC(=O)c2sc3ncccc3c2-c2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H14F2N2OS/c22-15-7-3-13(4-8-15)12-25-20(26)19-18(14-5-9-16(23)10-6-14)17-2-1-11-24-21(17)27-19/h1-11H,12H2,(H,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 311n/an/an/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membrane preparation

Bioorg Med Chem Lett 24: 3845-9 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.057
BindingDB Entry DOI: 10.7270/Q2HH6MR1
More data for this
Ligand-Target Pair