BDBM50050487 10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol::CHEMBL431947

SMILES: COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2

InChI Key: InChIKey=LMPYGANIBIHENG-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu opioid receptor (CALF)	BDBM50050487 (10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...) Show SMILES COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2 |THB:17:16:20:11.5.4,10:11:20:16.15.14| Show InChI InChI=1S/C18H27NO2/c1-17-8-7-16(19(2)3)18(11-17,12-21-4)10-13-5-6-14(20)9-15(13)17/h5-6,9,16,20H,7-8,10-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Mu opioid receptor (CALF)	BDBM50050487 (10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...) Show SMILES COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2 |THB:17:16:20:11.5.4,10:11:20:16.15.14| Show InChI InChI=1S/C18H27NO2/c1-17-8-7-16(19(2)3)18(11-17,12-21-4)10-13-5-6-14(20)9-15(13)17/h5-6,9,16,20H,7-8,10-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50050487 (10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...) Show SMILES COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2 |THB:17:16:20:11.5.4,10:11:20:16.15.14| Show InChI InChI=1S/C18H27NO2/c1-17-8-7-16(19(2)3)18(11-17,12-21-4)10-13-5-6-14(20)9-15(13)17/h5-6,9,16,20H,7-8,10-12H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50050487 (10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...) Show SMILES COCC12Cc3ccc(O)cc3C(C)(CCC1N(C)C)C2 |THB:17:16:20:11.5.4,10:11:20:16.15.14| Show InChI InChI=1S/C18H27NO2/c1-17-8-7-16(19(2)3)18(11-17,12-21-4)10-13-5-6-14(20)9-15(13)17/h5-6,9,16,20H,7-8,10-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair