BindingDB PrimarySearch

BDBM50050515 Boronic acid derivative::CHEMBL63652

SMILES: N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key: InChIKey=BMCGYCXNUMDZSH-RYUDHWBXSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50050515
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro for inhibition of Dipeptidylpeptidase IV.				J Med Chem 39: 2087-94 (1996) Article DOI: 10.1021/jm950732f BindingDB Entry DOI: 10.7270/Q29Z95K5
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
DPP8/9 (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dipeptidyl peptidase II (DPP2) (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Homeobox protein PKNOX1 (Human)	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50050515 (Boronic acid derivative \| CHEMBL63652 \| US11096924...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1B(O)O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair