BDBM50050704 (R)-4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid::(R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid::CHEMBL47277

SMILES: OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1

InChI Key: InChIKey=CUVGUPIVTLGRGI-SSDOTTSWSA-N

Data: 3 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50050704 ((R)-4-(3-Phosphono-propyl)-piperazine-2-carboxylic...) Show SMILES OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1 |r| Show InChI InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50050704 ((R)-4-(3-Phosphono-propyl)-piperazine-2-carboxylic...) Show SMILES OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1 |r| Show InChI InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50050704 ((R)-4-(3-Phosphono-propyl)-piperazine-2-carboxylic...) Show SMILES OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1 |r| Show InChI InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)