BDBM50050745 CHEMBL45994::N-[(1S,2R)-2-(3-Methoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-2,2-diphenyl-acetamide

SMILES: COc1cccc(c1)[C@H]1CCc2ccccc2[C@H]1NC(=O)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=ZFRGDGGCVIMPFS-PQHLKRTFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50050745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50050745 (CHEMBL45994 | N-[(1S,2R)-2-(3-Methoxy-phenyl)-1,2,...) Show SMILES COc1cccc(c1)[C@H]1CCc2ccccc2[C@H]1NC(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H29NO2/c1-34-26-17-10-16-25(21-26)28-20-19-22-11-8-9-18-27(22)30(28)32-31(33)29(23-12-4-2-5-13-23)24-14-6-3-7-15-24/h2-18,21,28-30H,19-20H2,1H3,(H,32,33)/t28-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against acyl-coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes.				J Med Chem 39: 1704-19 (1996) Article DOI: 10.1021/jm950833d BindingDB Entry DOI: 10.7270/Q2QN65V7
					More data for this Ligand-Target Pair