BDBM50050855 CHEMBL3318008

SMILES: CCNC(=O)Nc1ccnc2cc(cnc12)-c1ccc(OC)c(OC)c1

InChI Key: InChIKey=XVYCWTBCNHCOBJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50050855 (CHEMBL3318008) Show SMILES CCNC(=O)Nc1ccnc2cc(cnc12)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,21,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50050855 (CHEMBL3318008) Show SMILES CCNC(=O)Nc1ccnc2cc(cnc12)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-14-7-8-21-15-9-13(11-22-18(14)15)12-5-6-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair