BDBM50051325 (5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(3-methoxy-phenyl)-amine::CHEMBL73301

SMILES: COc1cccc(Nc2ncnc3[nH]c(C)c(C)c23)c1

InChI Key: InChIKey=QBIWREUCGXFGJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50051325 ((5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(3-...) Show SMILES COc1cccc(Nc2ncnc3[nH]c(C)c(C)c23)c1 Show InChI InChI=1S/C15H16N4O/c1-9-10(2)18-14-13(9)15(17-8-16-14)19-11-5-4-6-12(7-11)20-3/h4-8H,1-3H3,(H2,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against epidermal growth factor receptor				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair