BDBM50051575 CHEMBL3337513

SMILES: Fc1ccccc1C1CCN(CC1)c1ccn(CC2CC2)c(=O)c1C#N

InChI Key: InChIKey=ZZVOMHKIFBKGKB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50051575 (CHEMBL3337513) Show SMILES Fc1ccccc1C1CCN(CC1)c1ccn(CC2CC2)c(=O)c1C#N Show InChI InChI=1S/C21H22FN3O/c22-19-4-2-1-3-17(19)16-7-10-24(11-8-16)20-9-12-25(14-15-5-6-15)21(26)18(20)13-23/h1-4,9,12,15-16H,5-8,10-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...				J Med Chem 57: 6495-512 (2014) Article DOI: 10.1021/jm500496m BindingDB Entry DOI: 10.7270/Q2DJ5H8J
					More data for this Ligand-Target Pair