BDBM50051582 CHEMBL3337519

SMILES: COc1ccccc1C1CCN(CC1)c1ccn(CC2CC2)c(=O)c1C#N

InChI Key: InChIKey=HRKXHGTUKIVFSS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50051582 (CHEMBL3337519) Show SMILES COc1ccccc1C1CCN(CC1)c1ccn(CC2CC2)c(=O)c1C#N Show InChI InChI=1S/C22H25N3O2/c1-27-21-5-3-2-4-18(21)17-8-11-24(12-9-17)20-10-13-25(15-16-6-7-16)22(26)19(20)14-23/h2-5,10,13,16-17H,6-9,11-12,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect incubated for 30 m...				J Med Chem 57: 6495-512 (2014) Article DOI: 10.1021/jm500496m BindingDB Entry DOI: 10.7270/Q2DJ5H8J
					More data for this Ligand-Target Pair