BDBM50051672 2-Phenyl-9-((R)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]indol-4-ylamine::2-Phenyl-9-(1-phenyl-ethyl)-9H-1,3,9-triaza-fluoren-4-ylamine::CHEMBL79415
SMILES: C[C@H](c1ccccc1)n1c2ccccc2c2c(N)nc(nc12)-c1ccccc1
InChI Key: InChIKey=VBCKEAQWAHLODG-MRXNPFEDSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50051672 (2-Phenyl-9-((R)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Julius-Maximilians-Universität Würzburg Curated by ChEMBL | Assay Description Radioligand binding assay for [3H]-PIA affinity towards Adenosine A1 receptor of rat cerebral cortical membrane | J Med Chem 39: 2482-91 (1996) Article DOI: 10.1021/jm960011w BindingDB Entry DOI: 10.7270/Q27H1HPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A1 receptor (BOVINE) | BDBM50051672 (2-Phenyl-9-((R)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Genova Curated by ChEMBL | Assay Description Binding affinity at bovine Adenosine A1 receptor. | J Med Chem 45: 4875-87 (2002) BindingDB Entry DOI: 10.7270/Q2N87BHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM50051672 (2-Phenyl-9-((R)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Julius-Maximilians-Universität Würzburg Curated by ChEMBL | Assay Description Radioligand binding assay for [3H]-NECA affinity towards adenosine A2A receptor of rat striatum | J Med Chem 39: 2482-91 (1996) Article DOI: 10.1021/jm960011w BindingDB Entry DOI: 10.7270/Q27H1HPH | |||||||||||
More data for this Ligand-Target Pair |