Found 7 hits for monomerid = 50051942 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 552 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of Aurora A (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase Aurora-C
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of Aurora C (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50051942
(CHEMBL3322563)Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10- | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University
Curated by ChEMBL
| Assay Description Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay |
Eur J Med Chem 84: 312-34 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7 |
More data for this Ligand-Target Pair | |