BDBM50052048 5-Allyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-one::CHEMBL328235

SMILES: C=CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1

InChI Key: InChIKey=ZKNFDJZITOUUHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50052048 (5-Allyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...) Show SMILES C=CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1 Show InChI InChI=1S/C21H17NO2/c1-2-14-21(16-9-4-3-5-10-16)20(23)18-12-8-15-22(18)17-11-6-7-13-19(17)24-21/h2-13,15H,1,14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Siena Curated by ChEMBL					Assay Description Compound was tested for Inhibition of HIV-1 RT activity.				J Med Chem 39: 2672-80 (1996) Article DOI: 10.1021/jm950702c BindingDB Entry DOI: 10.7270/Q21R6PM4
					More data for this Ligand-Target Pair