BDBM50052085 1-Butyl-4-(7-ethoxy-2,3-bis-hydroxymethyl-5-methoxy-naphthalen-1-yl)-3,6-dihydro-1H-pyridin-2-one::CHEMBL91042

SMILES: CCCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2c(OC)cc(OCC)cc12

InChI Key: InChIKey=GLUBDWKKNWGCBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052085   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052085 (1-Butyl-4-(7-ethoxy-2,3-bis-hydroxymethyl-5-methox...) Show SMILES CCCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2c(OC)cc(OCC)cc12 |c:6| Show InChI InChI=1S/C24H31NO5/c1-4-6-8-25-9-7-16(11-23(25)28)24-20-12-18(30-5-2)13-22(29-3)19(20)10-17(14-26)21(24)15-27/h7,10,12-13,26-27H,4-6,8-9,11,14-15H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair