BDBM50052086 6-(6,7-Bis-hydroxymethyl-2,3-dimethoxy-naphthalen-1-yl)-1-methyl-3,6-dihydro-1H-pyridin-2-one::CHEMBL329876

SMILES: COc1cc2cc(CO)c(CO)cc2c(C2C=CCC(=O)N2C)c1OC

InChI Key: InChIKey=BBPVPWNUFRIWDB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052086 (6-(6,7-Bis-hydroxymethyl-2,3-dimethoxy-naphthalen-...) Show SMILES COc1cc2cc(CO)c(CO)cc2c(C2C=CCC(=O)N2C)c1OC |c:17| Show InChI InChI=1S/C20H23NO5/c1-21-16(5-4-6-18(21)24)19-15-8-14(11-23)13(10-22)7-12(15)9-17(25-2)20(19)26-3/h4-5,7-9,16,22-23H,6,10-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair