BDBM50052091 CHEMBL92491::[3-Hydroxymethyl-6-methoxy-1-(3,4,5-trimethoxy-phenyl)-naphthalen-2-yl]-methanol

SMILES: COc1ccc2c(c(CO)c(CO)cc2c1)-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=SRVNQPFSGYJCGC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052091 (CHEMBL92491 | [3-Hydroxymethyl-6-methoxy-1-(3,4,5-...) Show SMILES COc1ccc2c(c(CO)c(CO)cc2c1)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H24O6/c1-25-16-5-6-17-13(8-16)7-15(11-23)18(12-24)21(17)14-9-19(26-2)22(28-4)20(10-14)27-3/h5-10,23-24H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair