BDBM50052092 CHEMBL313143::[3-Hydroxymethyl-6,7-dimethoxy-1-(3,4,5-trimethoxy-benzyl)-naphthalen-2-yl]-methanol

SMILES: COc1cc(Cc2c(CO)c(CO)cc3cc(OC)c(OC)cc23)cc(OC)c1OC

InChI Key: InChIKey=BEEBPLQQLLJJLJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052092 (CHEMBL313143 | [3-Hydroxymethyl-6,7-dimethoxy-1-(3...) Show SMILES COc1cc(Cc2c(CO)c(CO)cc3cc(OC)c(OC)cc23)cc(OC)c1OC Show InChI InChI=1S/C24H28O7/c1-27-20-10-15-9-16(12-25)19(13-26)18(17(15)11-21(20)28-2)6-14-7-22(29-3)24(31-5)23(8-14)30-4/h7-11,25-26H,6,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair