BDBM50052093 CHEMBL91728::[7-Hydroxymethyl-5-(3,4,5-trimethoxy-phenyl)-naphtho[2,3-d][1,3]dioxol-6-yl]-methanol

SMILES: COc1cc(cc(OC)c1OC)-c1c(CO)c(CO)cc2cc3OCOc3cc12

InChI Key: InChIKey=NKLQUWSIESICQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052093 (CHEMBL91728 | [7-Hydroxymethyl-5-(3,4,5-trimethoxy...) Show SMILES COc1cc(cc(OC)c1OC)-c1c(CO)c(CO)cc2cc3OCOc3cc12 Show InChI InChI=1S/C22H22O7/c1-25-19-6-13(7-20(26-2)22(19)27-3)21-15-8-18-17(28-11-29-18)5-12(15)4-14(9-23)16(21)10-24/h4-8,23-24H,9-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair