BDBM50052096 4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen-1-yl)-1-(2-methoxy-ethyl)-3,6-dihydro-1H-pyridin-2-one::CHEMBL90469

SMILES: COCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2cc(OC)c(OC)cc12

InChI Key: InChIKey=IDYGYFZRZDPUOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052096 (4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen-...) Show SMILES COCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2cc(OC)c(OC)cc12 |c:6| Show InChI InChI=1S/C22H27NO6/c1-27-7-6-23-5-4-14(10-21(23)26)22-17-11-20(29-3)19(28-2)9-15(17)8-16(12-24)18(22)13-25/h4,8-9,11,24-25H,5-7,10,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair