BDBM50052097 5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen-1-yl)-2,3-dimethoxy-N,N-dimethyl-benzamide::CHEMBL90059

SMILES: COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(c3)C(=O)N(C)C)c2cc1OC

InChI Key: InChIKey=HLSOZRYDNZEYOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052097 (5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen-...) Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(c3)C(=O)N(C)C)c2cc1OC Show InChI InChI=1S/C25H29NO7/c1-26(2)25(29)18-8-15(10-22(32-5)24(18)33-6)23-17-11-21(31-4)20(30-3)9-14(17)7-16(12-27)19(23)13-28/h7-11,27-28H,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair