BDBM50052099 1-Butyl-4-(6,7-diethoxy-2,3-bis-hydroxymethyl-naphthalen-1-yl)-3,6-dihydro-1H-pyridin-2-one::CHEMBL327834

SMILES: CCCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2cc(OCC)c(OCC)cc12

InChI Key: InChIKey=XAEPFDVBAVYYLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052099 (1-Butyl-4-(6,7-diethoxy-2,3-bis-hydroxymethyl-naph...) Show SMILES CCCCN1CC=C(CC1=O)c1c(CO)c(CO)cc2cc(OCC)c(OCC)cc12 |c:6| Show InChI InChI=1S/C25H33NO5/c1-4-7-9-26-10-8-17(13-24(26)29)25-20-14-23(31-6-3)22(30-5-2)12-18(20)11-19(15-27)21(25)16-28/h8,11-12,14,27-28H,4-7,9-10,13,15-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
					More data for this Ligand-Target Pair