BDBM50052540 1-(4-Fluoro-phenyl)-4-(4-pyridin-3-yl-but-3-ynyl)-piperazine::CHEMBL110843

SMILES: Fc1ccc(cc1)N1CCN(CCC#Cc2cccnc2)CC1

InChI Key: InChIKey=KPSYTMDZRNIFGA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50052540 (1-(4-Fluoro-phenyl)-4-(4-pyridin-3-yl-but-3-ynyl)-...) Show SMILES Fc1ccc(cc1)N1CCN(CCC#Cc2cccnc2)CC1 Show InChI InChI=1S/C19H20FN3/c20-18-6-8-19(9-7-18)23-14-12-22(13-15-23)11-2-1-4-17-5-3-10-21-16-17/h3,5-10,16H,2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D2 in rat striatal membrane by [3H]-spiperone displacement.				J Med Chem 39: 3179-87 (1996) Article DOI: 10.1021/jm950721m BindingDB Entry DOI: 10.7270/Q23N22GZ
					More data for this Ligand-Target Pair