BDBM50052548 1-(4-Benzofuran-5-yl-but-3-ynyl)-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL419021

SMILES: C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2occc2c1

InChI Key: InChIKey=SAPVVBMVHBHWPK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50052548 (1-(4-Benzofuran-5-yl-but-3-ynyl)-4-phenyl-1,2,3,6-...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2occc2c1 |c:5| Show InChI InChI=1S/C23H21NO/c1-2-7-20(8-3-1)21-11-15-24(16-12-21)14-5-4-6-19-9-10-23-22(18-19)13-17-25-23/h1-3,7-11,13,17-18H,5,12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	437	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 of rat striatal membrane was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50052548 (1-(4-Benzofuran-5-yl-but-3-ynyl)-4-phenyl-1,2,3,6-...) Show SMILES C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2occc2c1 |c:5| Show InChI InChI=1S/C23H21NO/c1-2-7-20(8-3-1)21-11-15-24(16-12-21)14-5-4-6-19-9-10-23-22(18-19)13-17-25-23/h1-3,7-11,13,17-18H,5,12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D2 in rat striatal membrane by [3H]-spiperone displacement.				J Med Chem 39: 3179-87 (1996) Article DOI: 10.1021/jm950721m BindingDB Entry DOI: 10.7270/Q23N22GZ
					More data for this Ligand-Target Pair