BDBM50052727 CHEMBL3318583

SMILES: Clc1cccc(c1)-c1ccc(cc1)C(=O)N1CC2CC1CN2c1ncccn1

InChI Key: InChIKey=AENWJYFHGDVCMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent proline transporter (Homo sapiens (Human))	BDBM50052727 (CHEMBL3318583) Show SMILES Clc1cccc(c1)-c1ccc(cc1)C(=O)N1CC2CC1CN2c1ncccn1 |TLB:22:21:16.15:18| Show InChI InChI=1S/C22H19ClN4O/c23-18-4-1-3-17(11-18)15-5-7-16(8-6-15)21(28)26-13-20-12-19(26)14-27(20)22-24-9-2-10-25-22/h1-11,19-20H,12-14H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human high-affinity L-proline transporter expressed in COS1 cells by [3H]proline uptake assay				Bioorg Med Chem Lett 24: 3886-90 (2014) Article DOI: 10.1016/j.bmcl.2014.06.049 BindingDB Entry DOI: 10.7270/Q20C4XDG
					More data for this Ligand-Target Pair