BDBM50052867 (R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL27940

SMILES: CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31

InChI Key: InChIKey=IVHTVHNCRZDRRG-MRXNPFEDSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50052867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity was measured on cloned Human 5-hydroxytryptamine 1A receptor which is labeled by [3H]-8-OH-DPAT				J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	38.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]-5-HT				J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human Dopamine receptor D2A				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity of the compound was measured on cloned Human D2A Receptor which is labeled by [3H]-Raclopride				J Med Chem 43: 1339-49 (2001) BindingDB Entry DOI: 10.7270/Q2RJ4HQ3
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50052867 ((R)-6,11-Dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[d...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1cccc(C)c-31 Show InChI InChI=1S/C18H19N/c1-12-5-3-7-14-11-16-18-13(9-10-19(16)2)6-4-8-15(18)17(12)14/h3-8,16H,9-11H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
					More data for this Ligand-Target Pair