BDBM50052924 2,4-Dichloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-benzamide::CHEMBL119638

SMILES: CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c2ccccc12

InChI Key: InChIKey=RVRBBMLDJGOSIK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AVPR1A (RAT)	BDBM50052924 (2,4-Dichloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahy...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c2ccccc12 Show InChI InChI=1S/C26H25Cl2N3O2/c1-30(2)23-8-5-15-31(24-7-4-3-6-21(23)24)26(33)17-9-12-19(13-10-17)29-25(32)20-14-11-18(27)16-22(20)28/h3-4,6-7,9-14,16,23H,5,8,15H2,1-2H3,(H,29,32)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from AVP-V1a receptor binding site in rat liver				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair
Vasopressin V2 Receptor (Rattus norvegicus (Rat))	BDBM50052924 (2,4-Dichloro-N-[4-(5-dimethylamino-2,3,4,5-tetrahy...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c2ccccc12 Show InChI InChI=1S/C26H25Cl2N3O2/c1-30(2)23-8-5-15-31(24-7-4-3-6-21(23)24)26(33)17-9-12-19(13-10-17)29-25(32)20-14-11-18(27)16-22(20)28/h3-4,6-7,9-14,16,23H,5,8,15H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from its AVP-V2 receptor binding site in rat kidney				J Med Chem 39: 3547-55 (1996) Article DOI: 10.1021/jm960133o BindingDB Entry DOI: 10.7270/Q2DZ07CT
					More data for this Ligand-Target Pair