BDBM50053060 (2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-carboxymethyl-pyrrolidine-2-carboxylic acid::CHEMBL331339
SMILES: CC(C)(C)c1ccc(cc1)C(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O
InChI Key: InChIKey=JTJNUMYICHRENL-UXLLHSPISA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus) | BDBM50053060 ((2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-car...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Inhibition of [3H]-kainate binding at rat forebrain ionotropic glutamate receptor kainate 2 | J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM50053060 ((2S,3S,4S)-4-[1-(4-tert-Butyl-phenyl)-vinyl]-3-car...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 263 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Inhibition of [3H]-kainate binding at ionotropic glutamate receptor kainate 2 | J Med Chem 39: 3617-24 (1996) Article DOI: 10.1021/jm960155a BindingDB Entry DOI: 10.7270/Q2WW7GRZ | |||||||||||
More data for this Ligand-Target Pair |