null

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1

InChI Key: InChIKey=ZJQBHEYWXVCZGD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50053415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50053415 (CHEMBL3318850) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O6/c63-51-21-17-49(18-22-51)61(33-41-71(42-34-61)37-9-11-57(75)47-13-25-53(65)26-14-47)79-59(77)31-29-55-45-73(69-67-55)39-7-5-3-1-2-4-6-8-40-74-46-56(68-70-74)30-32-60(78)80-62(50-19-23-52(64)24-20-50)35-43-72(44-36-62)38-10-12-58(76)48-15-27-54(66)28-16-48/h13-28,45-46H,1-12,29-44H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2long receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50053415 (CHEMBL3318850) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O6/c63-51-21-17-49(18-22-51)61(33-41-71(42-34-61)37-9-11-57(75)47-13-25-53(65)26-14-47)79-59(77)31-29-55-45-73(69-67-55)39-7-5-3-1-2-4-6-8-40-74-46-56(68-70-74)30-32-60(78)80-62(50-19-23-52(64)24-20-50)35-43-72(44-36-62)38-10-12-58(76)48-15-27-54(66)28-16-48/h13-28,45-46H,1-12,29-44H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2short receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50053415 (CHEMBL3318850) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O6/c63-51-21-17-49(18-22-51)61(33-41-71(42-34-61)37-9-11-57(75)47-13-25-53(65)26-14-47)79-59(77)31-29-55-45-73(69-67-55)39-7-5-3-1-2-4-6-8-40-74-46-56(68-70-74)30-32-60(78)80-62(50-19-23-52(64)24-20-50)35-43-72(44-36-62)38-10-12-58(76)48-15-27-54(66)28-16-48/h13-28,45-46H,1-12,29-44H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM50053415 (CHEMBL3318850) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O6/c63-51-21-17-49(18-22-51)61(33-41-71(42-34-61)37-9-11-57(75)47-13-25-53(65)26-14-47)79-59(77)31-29-55-45-73(69-67-55)39-7-5-3-1-2-4-6-8-40-74-46-56(68-70-74)30-32-60(78)80-62(50-19-23-52(64)24-20-50)35-43-72(44-36-62)38-10-12-58(76)48-15-27-54(66)28-16-48/h13-28,45-46H,1-12,29-44H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from porcine striatal membranes D1 receptor by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50053415 (CHEMBL3318850) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O6/c63-51-21-17-49(18-22-51)61(33-41-71(42-34-61)37-9-11-57(75)47-13-25-53(65)26-14-47)79-59(77)31-29-55-45-73(69-67-55)39-7-5-3-1-2-4-6-8-40-74-46-56(68-70-74)30-32-60(78)80-62(50-19-23-52(64)24-20-50)35-43-72(44-36-62)38-10-12-58(76)48-15-27-54(66)28-16-48/h13-28,45-46H,1-12,29-44H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D4.4 receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair