BDBM50053578 CHEMBL3326369

SMILES: CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C#N

InChI Key: InChIKey=MIQLXHJZYKEPHF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053578 (CHEMBL3326369) Show SMILES CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C#N Show InChI InChI=1S/C13H13N5O2/c1-2-17-12(19)9-5-7(6-14)10(15)16-11(9)18(13(17)20)8-3-4-8/h5,8H,2-4H2,1H3,(H2,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
					More data for this Ligand-Target Pair