BDBM50053589 (S)-3-Hydroxyphenylglycine::(S)-Amino-(3-hydroxy-phenyl)-acetic acid::3HPG::CHEMBL442347

SMILES: N[C@H](C(O)=O)c1cccc(O)c1

InChI Key: InChIKey=DQLYTFPAEVJTFM-ZETCQYMHSA-N

Data: 12 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50053589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP Ki Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP Ki Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP Ki Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Curated by PDSP Ki Database									J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ
					More data for this Ligand-Target Pair
Glutamate receptor 3 (RAT)	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by PDSP Ki Database									Eur J Pharmacol 267: 77-84 (1994) Article DOI: 10.1016/0922-4106(94)90227-5 BindingDB Entry DOI: 10.7270/Q2RX99MZ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50053589 ((S)-3-Hydroxyphenylglycine | (S)-Amino-(3-hydroxy-...) Show SMILES N[C@H](C(O)=O)c1cccc(O)c1 Show InChI InChI=1S/C8H9NO3/c9-7(8(11)12)5-2-1-3-6(10)4-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a
Università di Perugia Curated by ChEMBL					Assay Description Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)				J Med Chem 39: 3998-4006 (1996) Article DOI: 10.1021/jm9601718 BindingDB Entry DOI: 10.7270/Q2765DFJ
					More data for this Ligand-Target Pair