BDBM50053734 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-2,2,5,5-tetramethyl-thiazolidin-4-one::CHEMBL130906

SMILES: COc1ccccc1N1CCN(CCCCN2C(=O)C(C)(C)SC2(C)C)CC1

InChI Key: InChIKey=NCRXJBDPIYXLQR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50053734 (3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C(C)(C)SC2(C)C)CC1 Show InChI InChI=1S/C22H35N3O2S/c1-21(2)20(26)25(22(3,4)28-21)13-9-8-12-23-14-16-24(17-15-23)18-10-6-7-11-19(18)27-5/h6-7,10-11H,8-9,12-17H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel, Inc. Curated by ChEMBL					Assay Description Binding affinity towards serotonin 5-HT1A receptor was determined in rat hippocampus using [3H]8-OH-DPAT as ligand				J Med Chem 39: 4044-57 (1996) Article DOI: 10.1021/jm960268u BindingDB Entry DOI: 10.7270/Q2ST7QH3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50053734 (3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C(C)(C)SC2(C)C)CC1 Show InChI InChI=1S/C22H35N3O2S/c1-21(2)20(26)25(22(3,4)28-21)13-9-8-12-23-14-16-24(17-15-23)18-10-6-7-11-19(18)27-5/h6-7,10-11H,8-9,12-17H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D2 was determined in rat striatal homogenate using [3H]- spiperone as radioligand				J Med Chem 39: 4044-57 (1996) Article DOI: 10.1021/jm960268u BindingDB Entry DOI: 10.7270/Q2ST7QH3
					More data for this Ligand-Target Pair